DEMOGRAPHICS, COMORBIDITIES, AND OUTCOMES OF SECONDARY PULMONARY HYPERTENSION IN YOUNG OBESE POPULATION: A NATIONAL INPATIENT ANALYSIS, 2017

TOPIC: Pulmonary Vascular Disease TYPE: Original Investigations PURPOSE: The role of obesity in outcomes pulmonary hypertension is controversial and data on young obese patients with secondary sparse. We aimed to assess the demographics, comorbidities, (SPH) population using a nationally representative cohort United States. METHODS: queried National Inpatient Sample (2017) used weighted identify hospitalizations among (18-44 years) SPH relevant ICD-10 codes. Patient-level sociodemographic characteristics pre-existing comorbidities were compared between vs. without SPH. Primary endpoints included all-cause mortality cardiopulmonary complications. Secondary length stay, patient disposition hospital charges. A two-tailed p<0.05 was considered statistically significant. RESULTS: Of 1,090,475 hospitalizations, 17,430 (1.6%) had Young obese-SPH often comprised older (38[33-42]], male (44.7% vs 24%), African American (44.1% 24.8%) who hospitalized non-electively (91.8% 71.1%) non-SPH cohort. consisted lower income quartile (45.7% 35.9%) urban teaching facility (76.2% 72%) admissions more associated rheumatoid arthritis/collagen vascular diseases (3.7% 1.5%), congestive heart failure (28.3% 2.7%), chronic disease (29% 14.9%), coagulopathy (7.3% 3.1%), (40.5% 27.2%), hyperlipidemia (23.4% 11.5%), smoking (39.8% 30.2%), uncomplicated diabetes (13.9% 8%) complications (19.4% 8.2%), fluid electrolyte disorders (35.3% 14.5%), kidney (17.3% 3.6%) valvular (6.6% 0.6%) showed higher odds (aOR 1.74, 95% CI 1.54-1.97), cor pulmonale 12.16, 10.90-13.56), embolism 3.76, 3.48-4.08), hemorrhage 1.97, 1.69-2.29), atrial fibrillation/flutter 2.59, 2.45-2.74), ventricular tachycardia 4.16, 3.83-4.52), 2.95, 2.40-3.62), supraventricular 2.70, 2.42-3.00), cardiac arrest 1.53, 1.29-1.81), cardiogenic shock 6.92 6.13-7.81), less discharged routinely (69.3% 87.8%) experienced extended stay (5 3 days) charges (45,228$ 24,266$) as CONCLUSIONS: In this nationwide analysis cardiovascular fatal found be alarmingly than that subsequently increased healthcare resource utilization cost. CLINICAL IMPLICATIONS: Hospitalization demonstrated concerning survival rate needs preemptive measures terms screening guidelines for management. DISCLOSURES: No relationships by Ummul Asfeen, source=Web Response Nilay Bhatt, Mounika Binkam, Rupak Desai, Zainab Gandhi, Jamila Begum Jabar Ali, Sonali Sachdeva, Pablo Tzorin, Ankit Vyas, Nibras Yar Khan,